In mammals norepinephrine (aka noradrenaline) is rapidly degraded to various metabolites. The principle metabolites are:
- Normetanephrine (via the enzyme catechol-O-methyl transferase, COMT)
- 3,4-Dihydroxymandelic acid (via monoamine oxidase, MAO)
- 3-Methoxy-4-hydroxymandelic acid (via MAO)
- 3-Methoxy-4-hydroxyphenylglycol (via MAO)
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