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A nicotinic agonist is a drug which enhances the action at the nicotinic acetylcholine receptor.

Examples include:

  • nicotine (by definition -- the "nicotinic acetylcholine receptor" is named for its affinity for nicotine)
  • epibatidine
  • lobeline
  • varenicline
Comparison
Agonist Receptor preference[1] Mechanism[1] Clinical use[1]
nicotine stimulation tobacco smoking cessation
lobeline stimulation
epibatidine stimulation none
suxamethonium Muscle type depolarization block muscle relaxant
decamethonium Muscle type depolarization block none
varenicline α4β2 partial agonist tobacco smoking cessation [2]

See also[]

External links[]



This page uses Creative Commons Licensed content from Wikipedia (view authors).
  1. 1.0 1.1 1.2 Unless else specified in table, then ref is: Rang, H. P. (2003). Pharmacology, Edinburgh: Churchill Livingstone. Page 149
  2. nlm.nih.gov
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