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Myalgia of the biceps brachii.jpg|
Myalgia
ICD-10 M791
ICD-9 729.1
OMIM [1]
DiseasesDB 22895
MedlinePlus [2]
eMedicine /
MeSH {{{MeshNumber}}}

Myalgia means "muscle pain" and is a symptom of many diseases and disorders. The most common causes are the overuse or over-stretching of a muscle or group of muscles. Myalgia without a traumatic history is often due to viral infections. Longer-term myalgias may be indicative of a metabolic myopathy, some nutritional deficiencies or chronic fatigue syndrome.

Causes[]

The most common causes of myalgia are overuse, injury or strain. However, myalgia can also be caused by diseases, disorders, medications, or as a response to a vaccination. It is also a sign of acute rejection after heart transplant surgery.

The most common causes are:

  • Injury or trauma, including sprains, hematoma
  • Overuse: using a muscle too much, too often, including protecting a separate injury
  • Chronic tension

Muscle pain occurs with:

  • Rhabdomyolysis, associated with:
    • Viral
    • Compression injury
    • Drug-related, esp fibrates and statins, occ ACE inhibitors, cocaine, some retro-viral drugs
    • Severe potassium deficiency
  • Fibromyalgia
  • Infections, including:
  • Auto-immune disorders, including
  • Systemic lupus erythematosus
  • Polymyalgia rheumatica
  • Polymyositis
  • Dermatomyositis
  • Multiple Sclerosis (this is neurologic pain localised to myotome)

Overuse[]

Overuse of a muscle is using it too much, too soon and/or too often.[1] Examples are:

Injury[]

The most common causes of myalgia by injury are: sprains and strain (injury).[1]

Autoimmune[]

Multiple sclerosis(neurologic pain interpreted as muscular), Myalgic Encephalomyelitis, Myositis, Lupus erythematosus, Familial Mediterranean fever, Polyarteritis nodosa, Devic's disease, Morphea

Metabolic defect[]

Carnitine palmitoyltransferase II deficiency, Conn's syndrome, Adrenal insufficiency, Hyperthyroidism, Hypothyroidism

Other[]

Chronic fatigue syndrome, Ehlers Danlos Syndrome, Hypokalemia, Exercise intolerance, Mastocytosis, Peripheral neuropathy, Eosinophilia myalgia syndrome, Fibromyalgia, Barcoo Fever, Herpes, Delayed onset muscle soreness, AIDS, HIV, Tumor-induced osteomalacia, Post Orgasmic Illness Syndrome

Medications[]

Acrylamide, Aspirin, colesevelam, darbepoetin, darunavir, daptomycin, ezetimibe, ibandronate sodium, ibuprofen, imiquimod, interferons, isotretinoin, procainamide, quinupristin/dalfopristin, statins, sumatriptan, tasigna, tiotropium, vardenafil, zolmitriptan, zocor.

Withdrawal syndromes[]

Sudden cessation of high-dose corticosteroids, opioids, barbiturates, benzodiazepines, or alcohol can induce myalgia.

See also[]

References[]

External links[]


Template:Myopathy



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