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Mitochondrial myopathy
ICD-10 G713
OMIM [1]
DiseasesDB [2]
MedlinePlus [3]
eMedicine /
MeSH {{{MeshNumber}}}

Mitochondrial myopathy is a type of myopathy associated with mitochondrial disease. On biopsy, the muscle tissue of patients with this disease usually demonstrate "ragged red" muscle fibers. These ragged-red fibers contain mild accumulations of glycogen and neutral lipids, and may show an increased reactivity for succinate dehydrogenase and a decreased reactivity for cytochrome c oxidase. Inheritance is maternal (non-Mendelian extranuclear). There are several subcategories of mitochondrial myopathies.


Although no cure currently exists, there is hope in treatment for this class of hereditary diseases with the use of an embryotic mitochondrial transplant.[1]

Signs and symptomsEdit

Signs and symptoms include:


  1. Three-parent embryo formed in lab. (web) Scientists believe they have made a potential breakthrough in the treatment of serious disease by creating a human embryo with three separate parents.. BBC News. URL accessed on 2008-02-08.

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