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The International Classification of Diseases for Oncology (ICD-O) is a domain specific extension of the International Statistical Classification of Diseases and Related Health Problems for tumor diseases. This classification is widely used by cancer registries Note not all categories are of interest to psychologists.

It is currently in its third revision (ICD-O-3). ICD-10 includes a list of morphology codes. They stem from ICD-O second edition (ICD-O-2) that was valid at the time of publication.


The classification has two axes: topography and morphology


The morphology axis is for the morphology of the tumor.

This axis has particular importance because the Systematized Nomenclature of Medicine ("SNOMED") has adopted the ICD-O classification of morphology. SNOMED has been changing continuously, and several different versions of SNOMED are in use. Accordingly, mapping of ICD-O codes to SNOMED requires careful assessment of whether entities are indeed true matches.

Examples of codes (ICD-O-3)Edit

(8000–8009) Not otherwise specifiedEdit

) Neoplasm, benign

) Neoplasm, uncertain whether benign or malignant

) Neoplasm, malignant

) Neoplasm, metastatic

) Neoplasm, malignant, uncertain whether primary or metastatic

(8010–8790) Epithelial Edit

) Squamous cell carcinoma, NOS

) Basal cell carcinoma, NOS

) Adenoma, NOS

) Adenocarcinoma, NOS

) Linitis plastica

) Insulinoma, NOS

) Glucagonoma, NOS

) Gastrinoma, NOS

) Vipoma

) Cholangiocarcinoma

) Hepatocellular carcinoma, NOS

) Adenoid cystic carcinoma

) Carcinoid tumor, NOS, of appendix

) Prolactinoma

) Oncocytoma

) Hurthle cell adenoma

) Renal cell carcinoma

) Grawitz tumor

) Multiple endocrine adenomas

) Endometrioid adenoma, NOS

) Cystadenoma, NOS

) Pseudomyxoma peritonei

) Warthin's tumor

) Thymoma, NOS

) Sex cord-stromal tumor

) Thecoma, NOS

) Granulosa cell tumor, NOS

) Arrhenoblastoma, NOS

) Sertoli-Leydig cell tumor

) Paraganglioma, NOS

) Pheochromocytoma, NOS

) Glomus tumor

) Melanocytic nevus

) Malignant melanoma, NOS

) Melanoma, NOS

) Nodular melanoma

) Dysplastic nevus

) Lentigo maligna melanoma

) Superficial spreading melanoma

) Acral lentiginous melanoma, malignant

) Melanoma, desmoplastic, amelanotic

(8800–9370) Connective tissueEdit

) Sarcoma, NOS

) Soft tissue sarcoma

) Desmoplastic small round cell tumor

) Fibroma, NOS

) Fibrosarcoma, NOS

) Myxoma, NOS

) Lipoma, NOS

) Liposarcoma, NOS

) Leiomyoma, NOS

) Leiomyosarcoma, NOS

) Myoma

) Myosarcoma

) Rhabdomyoma, NOS

) Rhabdomyosarcoma, NOS

) Pleomorphic adenoma

) Nephroblastoma, NOS (Wilms's tumor)

) Brenner tumor, NOS

) Synovial sarcoma, NOS

) Mesothelioma, benign

) Mesothelioma, NOS

) Dysgerminoma

) Germ cell tumor, NOS

) Embryonal carcinoma, NOS

) Yolk sac tumor

) Teratoma, benign

) Teratoma, malignant, NOS

) Dermoid cyst, NOS

) Choriocarcinoma, NOS

) Hemangioma, NOS

) Angioma, NOS

) Hemangiosarcoma

) Angiosarcoma

) Hemangioendothelioma, benign

) Hemangioendothelioma, NOS

) Kaposi's sarcoma

) Hemangiopericytoma, benign

) Hemangiopericytoma, NOS

) Lymphangioma, NOS

) Cystic lymphangioma

) Osteoma, NOS

) Osteosarcoma, NOS

) Osteochondroma

) Cartilaginous exostosis

) Chondroma, NOS

) Chondrosarcoma, NOS

) Ewing's sarcoma

) Cementoblastoma, benign

) Ameloblastoma, NOS

) Craniopharyngioma

(9380–9589) Nervous systemEdit

) Mixed oligoastrocytoma

) Ependymoma, NOS

) Astrocytoma, NOS

) Oligodendroglioma, NOS

) Neuroblastoma, NOS

) Retinoblastoma

) Neurofibroma, NOS

) Neurofibromatosis, NOS

) Schwannoma, NOS

) Neurinoma

) Acoustic neuroma

) Neuroma, NOS

(9590–9999) Hematologic (Leukemias, Lymphomas and related disorders)Edit

) Lymphoma, NOS

) Non-Hodgkin's lymphoma, NOS

) Lymphosarcoma, NOS

) Hodgkin's disease, NOS

) Lymphocyte-rich classical Hodgkin lymphoma

) Mixed cellularity classical Hodgkin lymphoma

) Lymphocyte-depleted classical Hodgkin lymphoma

) Nodular lymphocyte predominant Hodgkin lymphoma

) Nodular sclerosis classical Hodgkin lymphoma

) Small lymphocytic lymphoma

) Lymphoplasmacytic lymphoma

) Mantle cell lymphoma

) Primary effusion lymphoma

) Mediastinal (thymic) large cell lymphoma

) Diffuse large B-cell lymphoma or Intravascular large B-cell lymphoma

) Burkitt lymphoma

) Splenic marginal zone lymphoma

) Follicular lymphoma

) Follicular lymphoma

) Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-lymphoma)

) Nodal marginal zone B-cell lymphoma

) Mycosis fungoides

) Sezary syndrome

) Peripheral T-cell lymphoma, unspecified

) Angioimmunoblastic T-cell lymphoma

) Subcutaneous panniculitis-like T-cell lymphoma

) Anaplastic large cell lymphoma

) Hepatosplenic T-cell lymphoma

) Enteropathy type T-cell lymphoma

) Lymphomatoid papulosis

) Primary cutaneous anaplastic large cell lymphoma

) Extranodal NK/T cell lymphoma, nasal type

) Blastic NK cell lymphoma

) Lymphoma

) Lymphoma

) Plasmacytoma, NOS or Extramedullary plasmacytoma or Solitary plasmacytoma of bone

) Multiple myeloma or Plasma cell myeloma

) Extraosseous plasmacytoma

) Mastocytoma, NOS or Extracutaneous mastocytoma

) Mast cell sarcoma

) Malignant mastocytosis or Indolent systemic mastocytosis

) Aggressive systemic mastocytosis or Systemic mastocytosis with associated clonal, hematological non-mast cell lineage disease

) Mast cell leukemia

) Langerhans cell histiocytosis

) Histiocytic sarcoma

) Langerhans cell sarcoma

) Dendritic cell sarcoma, NOS or Interdigitating dendritic cell sarcoma/tumor

) Follicular dendritic cell sarcoma/tumor

) Waldenstrom macroglobulinemia

) Lymphomatoid granulomatosis

-- Lymphoid leukemias, and related conditionsEdit

) Leukemia, NOS

) Acute leukemia of ambiguous lineage

) Acute leukemia, NOS

) Lymphocytic leukemia, NOS

) Lymphatic leukemia, NOS

) Acute lymphoblastic leukemia, NOS

) Acute lymphocytic leukemia

) Chronic lymphocytic leukemia

) Leukemia

) Adult T-cell leukemia/lymphoma

) T-cell large granular lymphocytic leukemia

) B-cell prolymphocytic leukemia

) T-cell prolymphocytic leukemia

) Precursor cell lymphoblastic leukemia, NOS

) Precursor B lymphoblastic leukemia

) Precursor T lymphoblastic leukemia

-- Myeloid leukemias, and related conditionsEdit

) Acute erythroid leukemia

) Myeloid leukemia, NOS

) Myelogenous leukemia, NOS

) Acute myelogenous leukemia (FAB-M1,M2)

) Chronic myelogenous leukemia

) Acute promyelocytic leukemia (FAB-M3)

) Acute promyelocytic leukemia (AML with t(15;17)(q22;q12), PML-RARa and variants)

) Acute myelomonocytic leukemia (FAB-M4)

) Basophilic leukemia or Acute basophilic leukemia

) AML with inv(16)(p13q22) or t(16;16)(p13;q22), CBFb/MYH11 (FAB M4Eo)

) Acute myeloid leukemia, minimally differentiated (FAB type M0)

) Acute myeloid leukemia, without maturation (FAB type M1)

) Acute myeloid leukemia, with maturation (FAB M2)

) Chronic myelogenous leukemia

) Atypical chronic myelogenous leukemia

) Eosinophilic leukemia

) Monocytic leukemia, NOS (FAB-M5)

) Acute monoblastic and monocytic leukemia (FAB M5)

) Acute myeloid leukemia multilineage dysplasia

) AML with t(8;21)(q22;q22), AML1/ETO

) AML with 11q23 (MLL) abnormalities

) Acute megakaryoblastic leukemia (FAB-M7)

) Acute myeloid leukemia and myelodysplastic syndrome, therapy related

) Chloroma or Myeloid sarcoma

) Acute panmyelosis with myelofibrosis

) Hairy cell leukemia

) Juvenile myelomonocytic leukemia

) Aggressive NK cell leukemia

-- OtherEdit

) Polycythemia vera

) Myeloproliferative disease, NOS

) Chronic idiopathic myelofibrosis

) Essential thrombocytemia

) Chronic neutrophilic leukemia

) Chronic eosinophilic leukemia / hypereosinophilic syndrome

) Post-transplant lymphoproliferative disorder, pleomorphic

) Chronic Myeloproliferative disease, unclassifiable

) Myelodysplastic / myeloproliferative diseases, unclassifiable

) Chronic myelomonocytic leukemia or Refractory anemia

) Refractory anemia with ringed sideroblasts

) Refractory anemia with excess blasts

) Refractory cytopenia with multilineage dysplasia

) Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality

) Myelodysplastic syndrome, NOS


The topography axis is for the topographical codes of the tumor's site. It is standardized with the C section of ICD-10

There were no changes in the topography axis between ICD-O-2 and ICD-O-3.

See List of ICD-10 codes#(C00–C97) Malignant Neoplasms for examples.

See alsoEdit

External linksEdit


Template:Epithelial neoplasms Template:Gonadal tumors, paraganglioma, glomus, nevi and melanomas Template:Skin tumors, nevi and melanomas Template:Soft tissue tumors and sarcomas Template:Germ cell tumors Template:Vascular tumors Template:Osseous and chondromatous tumors Template:Odontogenic tumors

Template:Hematological malignancy histology Template:Myeloid malignancy

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