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Glucose metabolism is an aspect of carbohydrate metabolism The most important carbohydrate is glucose, a simple sugar (monosaccharide) that is metabolized by nearly all known organisms.

Metabolic pathways[]


Glycolysis Metabolic Pathway
Glucose Glucose-6-phosphate Fructose 6-phosphate Fructose 1,6-bisphosphate Dihydroxyacetone phosphate Glyceraldehyde 3-phosphate Glyceraldehyde 3-phosphate
D-glucose wpmp ATP ADP Alpha-D-glucose-6-phosphate wpmp Beta-D-fructose-6-phosphate wpmp ATP ADP Beta-D-fructose-1,6-bisphosphate wpmp Glycerone-phosphate wpmp D-glyceraldehyde-3-phosphate wpmp D-glyceraldehyde-3-phosphate wpmp NAD+ + Pi NADH + H+
Biochem reaction arrow foward YYNN horiz med Biochem reaction arrow reversible NNNN horiz med Biochem reaction arrow foward YYNN horiz med Biochem reaction arrow reversible NNNN horiz med + Biochem reaction arrow reversible NNNN horiz med 2 Biochem reaction arrow reversible YYYY horiz med
NAD+ + Pi NADH + H+
1,3-Bisphosphoglycerate 3-Phosphoglycerate 2-Phosphoglycerate Phosphoenolpyruvate Pyruvate Acetyl-CoA
1,3-bisphospho-D-glycerate wpmp ADP ATP 3-phospho-D-glycerate wpmp 2-phospho-D-glycerate wpmp H2O Phosphoenolpyruvate wpmp ADP ATP Pyruvate wpmp CoA + NAD+ NADH + H+ + CO2 Acetyl co-A wpmp
2 Biochem reaction arrow reversible YYYY horiz med 2 Biochem reaction arrow reversible NNNN horiz med 2 Biochem reaction arrow reversible NYYN horiz med 2 Biochem reaction arrow foward YYNN horiz med 2 Biochem reaction arrow foward YYNN horiz med 2
ADP ATP H2O


Glucoregulation[]

Glucoregulation is the maintenance of steady levels of glucose in the body; it is part of homeostasis, and keeps a constant internal environment around cells in the body.

The hormone insulin makes the body convert glucose into glycogen and puts it into the liver; the insulin is made in the pancreas, and is secreted when the blood sugar is too high. Insulin also promotes the use of glucose by the muscles.

The hormone glucagon, on the other hand, acts in the opposite direction and promotes the conversion of glycogen to glucose in response to low blood sugar.

Human diseases of glucose metabolism[]

See also[]

External links[]

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