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Bursting is a rapid signaling mode in neurons whereby clusters of two or more action potentials are emitted as a single signaling event. Burst mode is thought to be useful for signaling important events and routing information in the brain. In general, there are two types of bursting:
- Input-driven bursting, where strong excitatory inputs produce a rapid activation and burst of action potentials
- Intrinsic bursting, where voltage-gated ion channels intrinsic to the neuron convert brief suprathreshold inputs into long-lasting bursts of action potential output.
Articles[edit | edit source]
- Switching Signals in the BrainPLoS Biology, 3(6):e210, 2005 June.
- Action potential burst mode transition mechanismPLoS Biology, 3(6):e175, 2005 June.
- Significance of action potential bursting Neurochemistry International Volume 41, Issue 5, 2002
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