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Biological inheritance is the process by which an offspring cell or organism acquires or becomes predisposed to characteristics of its parent cell or organism. Through inheritance, variations exhibited by individuals can accumulate and cause a species to evolve.
In general terms inheritance occurs as the outcome of three processes:
- Genetic or Mendelian inheritance results from DNA replication and cell division.
- Epigenetic inheritance results from, among other things, DNA modifications such as gene silencing.
- non-Mendelian inheritance includes inheritance based on cytoplasmic substituents, including mitochondria and chloroplasts.
More specifically a description of a mode of biological inheritance consists of three main categories:
- 1. Number of involved Loci
- 2. Involved Chromosomes
- -Autosomal - Loci are not situated on a sex chromosome
- -Gonosomal - Loci are situated on a sex chromosome
- -Mitochondrial - Loci are situated on the mitochondrial DNA
These three categories are part of every exact description of a mode of inheritance in the above order. Additionally, more specifications may be added as follows:
- Coincidental and environmental interactions
- -Incomplete (percentual number)
- -Heritability (in polygenetic and sometimes also in oligogenetic modes of inheritance)
- -Maternal or paternal imprinting phenomena (also see epigenetics)
- Gender interactions
- -Sex-linked inheritance (Gonosomal Loci)
- -Sex-limited phenotype expression (e.g. Cryptorchism)
- -Inheritance through the maternal line (in case of Mitochondrial DNA loci)
- -Inheritance through the paternal line (in case of Y-chromosomal loci)
- -Epistasis with other Loci (e.g. overdominance)
- -Gene coupling with other Loci (also see Crossing over)
- -Homozygotous lethal factors
- -Semi-lethal factors
Determination and description of a mode of inheritance is primarily achieved through statistical analysis of pedigree data. In case the involved loci are known, methods of molecular genetics can also be employed.
Literature[edit | edit source]
Ruvinsky and Sampson (2001) The Genetics of the Dog; CABI Publishing, Wallingford/New York.
Srb, Owen and Edgar (1965) General Genetics; Freeman & Company, San Francisco.
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