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Brain: Basal optic nucleus of Meynert
Latin n. basalis telencephali
Gray's subject #
Part of
BrainInfo/UW hier-257
MeSH A08.186.211.730.885.105.880.100

In the lateral part of the tuber cinereum is a nucleus of nerve cells, the basal optic nucleus of Meynert.

The basal nucleus of Meynert (NBM) is involved in production of acetylcholine. A decrease in this production is seen in Alzheimer's disease and Lewy body dementia, leading to a general decrease of mental capacity and learning. Most pharmacological treatments of dementia focus on compensating for a faltering NBM function through artificially increasing acetylcholine levels.

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  • Weinberger, N. M. (1998). Tuning the brain by learning and by stimulation of the nucleus basalis , Trends in Cognitive Sciences 2, 271-3

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This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.