Paul R. McHugh

Paul R. McHugh, born 1931, Lawrence, Massachusetts, the son of a Lowell High School teacher and a homemaker, is an American psychiatrist, researcher, and educator. He is University Distinguished Professor of Psychiatry at the Johns Hopkins University School of Medicine and the author, co-author, or editor of seven books within his field.

Education
Paul Rodney McHugh was born in 1931 in Lawrence, Massachusetts. He graduated from Harvard College in 1952 and from Harvard Medical School in 1956. While at Harvard he was "introduced to and ultimately directed away from the Freudian school of psychiatry."

Following medical school, McHugh's education was influenced by George Thorn, the Physician-in-Chief at the Harvard-affiliated Peter Bent Brigham Hospital (now Brigham and Women's Hospital). Thorn was disillusioned with Freudian psychiatry and felt that those who devoted themselves to it became single-minded, failing to grow as doctors. Thorn encouraged McHugh to develop a different career path, suggesting that he enter the field of psychiatry by first studying neurology. At Thorn's recommendation, McHugh was accepted into the neurology and neuropathology residency program at the Massachusetts General Hospital where he studied for three years under Dr. Raymond Adams, the chief of the Neurology Department.

From Massachusetts General, McHugh went to the Institute of Psychiatry in London (where he studied under Sir Aubrey Lewis and was supervised by James Gibbons and Gerald Russell). Following his year in London, McHugh went to the Division of Neuropsychiatry at Walter Reed Army Institute of Research.

Career
After his training, McHugh held various academic and administrative positions: Professor of Psychiatry at Cornell UniversitySchool of Medicine (where he founded the Bourne Behavioral Research Laboratory), Clinical Director and Director of Residency Education at the New York Hospital Westchester Division; Professor and Chairman of the Department of Psychiatry at the Oregon Health Sciences Center at the University of Oregon.

From 1975 till 2001, McHugh was the Henry Phipps Professor of Psychiatry and the director of the Department of Psychiatry and Behavioral Science at the Johns Hopkins University. At the same time, he was psychiatrist-in-chief at the Johns Hopkins Hospital. He is currently University Distinguished Service Professor of Psychiatry at Johns Hopkins University School of Medicine.

His own research has focused on the neuroscientific foundations of motivated behaviors, psychiatric genetics, epidemiology, and neuropsychiatry.

During the 1960s, McHugh co-authored papers on hydrocephalus, depression and suicide, and amygdaloid stimulation.

In 1975, McHugh co-authored (along with M. F. Folstein and S. E. Folstein) a paper entitled "Mini-Mental State: A Practical Method for Grading the Cognitive State of Patients for the Clinician." This paper details the Mini Mental State Exam (MMSE), an exam consisting of just eleven questions, that quickly and accurately assesses patients for signs of dementia and other states of cognitive impairment. It is one of the most widely used tests in the mental health field.

In 1979, in his capacity as chair of the Department of Psychiatry, McHugh closed down the gender identity clinic at Johns Hopkins Hospital.

In 1983, McHugh and colleague Phillip R. Slavney co-authored The Perspectives of Psychiatry, which presents the Johns Hopkins approach to psychiatry. The book "seeks to systematically apply the best work of behaviorists, psychotherapists, social scientists and other specialists long viewed as at odds with each other." A second edition was published in 1998.

In 1992, McHugh treated the then-president of The American University, Richard Berendzen who'd been accused of making obscene phone calls to a 16-year-old baby sitter in Washington, D.C.

McHugh also treated author Tom Wolfe for depression suffered following coronary bypass surgery. Wolfe dedicated his 1998 novel, A Man in Full to McHugh, “whose brilliance, comradeship and unfailing kindness saved the day.”

In 1992, McHugh announced that he was going to leave Johns Hopkins and accept a position as director and CEO of Friends Hospital in Philadelphia. The Johns Hopkins School of Medicine quickly sought to retain him and was successful in doing so.

Throughout the decade of the 1990s, McHugh was active in debunking the idea of recovered memory—that is, the idea that people could suddenly and spontaneously remember childhood sexual abuse.

In 2001, McHugh was appointed by President George W. Bush to the Presidential Council on Bioethics. The Council was charged with the task of making recommendations as to what the U.S. federal government's policy regarding embryonic stem cells should be. McHugh was against using new lines of embryonic stem cells derived from in vitro fertilization but was in favor of the use of stem cells derived from somatic cell nuclear transfer (SCNT). In SCNT, the nucleus of a cell is removed and replaced by another cell nucleus. McHugh felt that cells created in this fashion could be regarded as tissue; whereas, stem cells taken from embryos caused the killing of an unborn child.

In 2002, McHugh was appointed to a lay panel assembled by the Roman Catholic Church to look into sexual abuse by priests.

In 2010, McHugh made a motion in United States District Court, Northern District of California, to file an amicus curiae brief in the case of Perry et al. v. Schwarzenegger et al. that stated in part: "Amicus seeks to provide information to this Court bearing on its decision of whether to endorse a legal declaration that orientation is a fixed and immutable characteristic similar to race or gender. In the proposed brief, Amicus points out two highly relevant facts: (1) there is no scientific consensus on what homosexuality is, and the number of people who fit in the class “gay and lesbian” varies widely, depending on which definition of homosexuality is used and (2) there is no scientific consensus that homosexuality is exclusively or primarily genetic in origin."

Theoretical Orientation
McHugh proposes that alterations in mental life be viewed from four perspectives:


 * 1) The perspective of disease: what is wrong with the structure of the brain itself?  Depression, schizophrenia and dementia are often viewed from the disease perpective.
 * 2) The perspective of dimension: in what way does an individual's character cause him trouble (e.g., extraversion/introversion, high IQ/low IQ)?
 * 3) The perspective of behavior:  what actions persist because they have been re-inforced, or are driven by biological means?  Addiction, obesity, or paraphilias are often seen from the behavior perspective.
 * 4) The perspective of life-story:  what has happened to a person which leads him to experience life as he does?  Grief is often viewed from the life-story perspective.

He opposes the symptom-only system of classification presented in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (editions III, III-R, IV, and IV-TR) on the grounds that it classifies mental disorders according to observation of signs and symptoms while not addressing underlying causes.

McHugh's theoretical orientation has led him to take controversial stands on a number of current psychiatric/medical issues including post traumatic stress disorder, multiple personality disorder (MPD) or dissociative identity disorder (DID), physician assisted suicide, and sexual reassignment surgery.

McHugh argues that multiple personality disorder (MPD; now known as dissociative identity disorder [DID]) is not, as has been maintained by some, a disorder in which a person actually has two or more distinct personalities. He further argues that MPD/DID is not "the linear consequence of child abuse" Instead, McHugh argues that MPD/DID is an artifact—a symptom or symptoms designed to garner medical attention or sympathy. Other such artifacts include conversion disorder, Briquet syndrome, and malingering.

McHugh generally opposes sexual reassignment surgery for both children and adults. With respect to male infants (i.e., those with the XY chromosome) born with genital malformation, McHugh feels that parents should refrain from deciding to surgically alter them to appear female. Instead, he feels that these children should be allowed to mature at which point they themselves can make an informed decision about what surgery to obtain, if any.

McHugh believes that adult males who wish to surgically alter themselves to appear anatomically female fall into two main groups: (1) "conflicted and guilt-ridden homosexual men" and (2) "heterosexual (and some bisexual) males who found intense sexual arousal in cross-dressing as females". McHugh, had several other impressions: First, "they [the transgendered individuals] were little changed in their psychological condition. They had much the same problems with relationships, work, and emotions as before. The hope that they would emerge now from their emotional difficulties to flourish psychologically had not been fulfilled". Second, they expressed little interest in and seemed indifferent to babies or children (typically female interests). Third, they came off as caricatures of the opposite sex.

Social, Political, and Religious Views
Paul McHugh is a practicing Catholic. He is a Democrat who describes himself as "religiously orthodox, politically liberal and culturally conservative -- a believer in marriage and the Marines, a supporter of institutions and family values."

Author

 * McHugh, P. R. (2006). Try to Remember: Psychiatry's Clash over Meaning, Memory, and Mind. New York: DANA.
 * ---. (2008). The Mind Has Mountains: Reflections on Society and Psychiatry. Baltimore, MD: Johns Hopkins University Press.

Co-Author

 * Hedblom, J. H., & McHugh, P. R. (2007). Last Call: Alcoholism and Recovery.
 * Fagan, P. J., & McHugh, P. R. Sexual Disorders: Perspectives on Diagnosis and Treatment.
 * Neubauer, D. N., & McHugh, P. R. Understanding Sleeplessness: Perspectives on Insomnia.
 * McHugh, P. R., & Slavney, P. R. (1998). The Perspectives of Psychiatry, 2nd ed. Baltimore, Maryland: Johns Hopkins University Press.

Editor

 * McHugh, P. R., & McKusick. Eds. (1990). Genes, Brain, and Behavior.

Peer Reviewed Journal Articles

 * Rosen GM, Spitzer RL, McHugh PR. Problems with the post-traumatic stress disorder diagnosis and its future in DSM V. Br J Psychiatry. 2008 Jan;192(1):3-4.PMID: 18174499
 * McCabe OL, Kaminsky MJ, McHugh PR. Clinical assessment in disaster mental health: a logic of case formulation. Am J Disaster Med. 2007 Nov-Dec;2(6):297-306. Review. PMID: 18297950
 * McHugh PR, Treisman G. PTSD: a problematic diagnostic category. J Anxiety Disord. 2007;21(2):211-22. Epub 2006 Nov 7. Review. PMID: 17085011
 * McHugh PR. Striving for coherence: psychiatry's efforts over classification. JAMA. 2005 May 25;293(20):2526-8.  PMID: 15914753
 * McHugh PR. Where's the wisdom? Cerebrum. 2004 Fall;6(4):27-8.  PMID: 15986532
 * McHugh PR. No veterinarian to "The naked ape" I. Cerebrum. 2004 Fall;6(4):19-24.  PMID: 15986530
 * McHugh PR, Lief HI, Freyd PP, Fetkewicz JM. From refusal to reconciliation: family relationships after an accusation based on recovered memories. J Nerv Ment Dis. 2004 Aug;192(8):525-31.PMID: 15387154
 * McHugh PR. The adventures of a "different" pair. Physiol Behav. 2004 Aug;82(1):171-4.PMID: 15234608
 * McHugh PR. Zygote and "clonote"--the ethical use of embryonic stem cells. N Engl J Med. 2004 Jul 15;351(3):209-11.  PMID: 15254278
 * McCabe OL, Gwon HS, McHugh PR, Breakey WR, Schwartz JM, Clark MR, Kaminsky MJ. Academic psychiatry and health care reform: strategic initiatives for sustaining the clinical mission. Psychiatr Serv. 2003 Feb;54(2):236-9.PMID: 12556606
 * Stephens JH, Richard P, McHugh PR. Long-term follow-up of patients with a diagnosis of paranoid state and hospitalized, 1913 to 1940. J Nerv Ment Dis. 2000 Apr;188(4):202-8.PMID: 10789996
 * Moran TH, Wirth JB, Schwartz GJ, McHugh PR. Interactions between gastric volume and duodenal nutrients in the control of liquid gastric emptying. Am J Physiol. 1999 Apr;276(4 Pt 2):R997-R1002.PMID: 10198377
 * McHugh PR. Dying made easy. Commentary. 1999 Feb;107(2):13-7.  PMID: 15986526
 * Stephens JH, Richard P, McHugh PR. Suicide in patients hospitalized for schizophrenia: 1913-1940. J Nerv Ment Dis. 1999 Jan;187(1):10-4.PMID: 9952248
 * Stephens JH, Richard P, McHugh PR. Long-term follow-up of patients hospitalized for schizophrenia, 1913 to 1940. J Nerv Ment Dis. 1997 Dec;185(12):715-21.PMID: 9442182
 * McHugh PR. Physician-assisted suicide—the ultimate right? N Engl J Med. 1997 May 22;336(21):1525; author reply 1526.  PMID: 9157280
 * McHugh PR. Hippocrates à la mode. Nat Med. 1996 May;2(5):507-9.  PMID: 8616701
 * Peyser CE, Folstein M, Chase GA, Starkstein S, Brandt J, Cockrell JR, Bylsma F, Coyle JT, McHugh PR, Folstein SE. Trial of d-alpha-tocopherol in Huntington's disease. Am J Psychiatry. 1995 Dec;152(12):1771-5.PMID: 8526244
 * McHugh PR, Putnam FW. Resolved: multiple personality disorder is an individually and socially created artifact. J Am Acad Child Adolesc Psychiatry. 1995 Jul;34(7):957-62; discussion 962-3.  PMID: 7649967
 * McHugh PR. Witches, multiple personalities, and other psychiatric artifacts. Nat Med. 1995 Feb;1(2):110-4.PMID: 7585001
 * McHugh PR. A "letter of experience" about faculty promotion in medical schools. Acad Med. 1994 Nov;69(11):877-81.PMID: 7945683
 * McHugh PR. Suicide and medical afflictions. Medicine (Baltimore). 1994 Nov;73(6):297-8.  PMID: 7984080
 * Cohen BJ, Nestadt G, Samuels JF, Romanoski AJ, McHugh PR, Rabins PV. Personality disorder in later life: a community study. Br J Psychiatry. 1994 Oct;165(4):493-9.PMID: 7804664
 * Salorio CF, Hammond PB, Schwartz GJ, McHugh PR, Moran TH. Age-dependent effects of CCK and devazepide in male and female rats. Physiol Behav. 1994 Oct;56(4):645-8.PMID: 7800726
 * Schwartz GJ, McHugh PR, Moran TH. Pharmacological dissociation of responses to CCK and gastric loads in rat mechanosensitive vagal afferents. Am J Physiol. 1994 Jul;267(1 Pt 2):R303-8.PMID: 8048636
 * Samuels JF, Nestadt G, Romanoski AJ, Folstein MF, McHugh PR. DSM-III personality disorders in the community. Am J Psychiatry. 1994 Jul;151(7):1055-62.PMID: 8010364
 * Nestadt G, Samuels JF, Romanoski AJ, Folstein MF, McHugh PR. Obsessions and compulsions in the community. Acta Psychiatr Scand. 1994 Apr;89(4):219-24.PMID: 8023687
 * McHugh PR. [The Professorial Promotions Committee of the Faculty of Medicine of Johns Hopkins: a letter of experience] Med Clin (Barc). 1994 Feb 26;102(7):259-66. Spanish.   PMID: 8170214
 * Nestadt G, Eaton WW, Romanoski AJ, Garrison R, Folstein MF, McHugh PR. Assessment of DSM-III personality structure in a general-population survey. Compr Psychiatry. 1994 Jan-Feb;35(1):54-63.PMID: 8149730
 * Lyketsos CG, Hanson A, Fishman M, McHugh PR, Treisman GJ. Screening for psychiatric morbidity in a medical outpatient clinic for HIV infection: the need for a psychiatric presence. Int J Psychiatry Med. 1994;24(2):103-13.PMID: 7960418
 * Treisman G, Fishman M, Lyketsos C, McHugh PR. Evaluation and treatment of psychiatric disorders associated with HIV infection. Res Publ Assoc Res Nerv Ment Dis. 1994;72:239-50.  PMID: 8115716
 * Schwartz GJ, McHugh PR, Moran TH. Gastric loads and cholecystokinin synergistically stimulate rat gastric vagal afferents. Am J Physiol. 1993 Oct;265(4 Pt 2):R872-6.PMID: 8238459
 * Moran TH, Ameglio PJ, Peyton HJ, Schwartz GJ, McHugh PR. Blockade of type A, but not type B, CCK receptors postpones satiety in rhesus monkeys. Am J Physiol. 1993 Sep;265(3 Pt 2):R620-4.PMID: 8214156
 * Treisman GJ, Lyketsos CG, Fishman M, Hanson AL, Rosenblatt A, McHugh PR. Psychiatric care for patients with HIV infection. The varying perspectives. Psychosomatics. 1993 Sep-Oct;34(5):432-9. Review.PMID: 7908136
 * Moran TH, Ameglio PJ, Schwartz GJ, Peyton HJ, McHugh PR. Endogenous cholecystokinin in the control of gastric emptying of liquid nutrient loads in rhesus monkeys. Am J Physiol. 1993 Aug;265(2 Pt 2):R371-5.PMID: 8368391
 * Schwartz GJ, Berkow G, McHugh PR, Moran TH. Gastric branch vagotomy blocks nutrient and cholecystokinin-induced suppression of gastric emptying. Am J Physiol. 1993 Mar;264(3 Pt 2):R630-7. Erratum in: Am J Physiol 1993 Jun;264(6 Pt 2):section R following table of contents. Am J Physiol 1993 Jun;264(6 Pt 3):section R followi. PMID: 8457019
 * Lyketsos CG, Hanson AL, Fishman M, Rosenblatt A, McHugh PR, Treisman GJ. Manic syndrome early and late in the course of HIV. Am J Psychiatry. 1993 Feb;150(2):326-7.PMID: 8422087
 * Nestadt G, Romanoski AJ, Samuels JF, Folstein MF, McHugh PR. The relationship between personality and DSM-III axis I disorders in the population: results from an epidemiological survey. Am J Psychiatry. 1992 Sep;149(9):1228-33.PMID: 1503137
 * McHugh PR. A structure for psychiatry at the century's turn—the view from Johns Hopkins. J R Soc Med. 1992 Aug;85(8):483-7. Review.  PMID: 1404200
 * Romanoski AJ, Folstein MF, Nestadt G, Chahal R, Merchant A, Brown CH, Gruenberg EM, McHugh PR. The epidemiology of psychiatrist-ascertained depression and DSM-III depressive disorders. Results from the Eastern Baltimore Mental Health Survey Clinical Reappraisal. Psychol Med. 1992 Aug;22(3):629-55.PMID: 1410089
 * Moran TH, Sawyer TK, Seeb DH, Ameglio PJ, Lombard MA, McHugh PR. Potent and sustained satiety actions of a cholecystokinin octapeptide analogue. Am J Clin Nutr. 1992 Jan;55(1 Suppl):286S-290S.PMID: 1728841
 * Moran TH, Ameglio PJ, Schwartz GJ, McHugh PR. Blockade of type A, not type B, CCK receptors attenuates satiety actions of exogenous and endogenous CCK. Am J Physiol. 1992 Jan;262(1 Pt 2):R46-50.PMID: 1733339
 * Schwartz GJ, Netterville LA, McHugh PR, Moran TH. Gastric loads potentiate inhibition of food intake produced by a cholecystokinin analogue. Am J Physiol. 1991 Nov;261(5 Pt 2):R1141-6.PMID: 1951762
 * Moran TH, Crosby RJ, McHugh PR. Effects of pylorectomy on cholecystokinin-induced inhibition of liquid gastric emptying. Am J Physiol. 1991 Sep;261(3 Pt 2):R531-5.PMID: 1887942
 * Schwartz GJ, McHugh PR, Moran TH. Integration of vagal afferent responses to gastric loads and cholecystokinin in rats. Am J Physiol. 1991 Jul;261(1 Pt 2):R64-9.PMID: 1858957
 * Nestadt G, Romanoski AJ, Brown CH, Chahal R, Merchant A, Folstein MF, Gruenberg EM, McHugh PR. DSM-III compulsive personality disorder: an epidemiological survey. Psychol Med. 1991 May;21(2):461-71.PMID: 1876651
 * Stephens JH, McHugh PR. Characteristics and long-term follow-up of patients hospitalized for mood disorders in the Phipps Clinic, 1913-1940. J Nerv Ment Dis. 1991 Feb;179(2):64-73.PMID: 1990073
 * Ladenheim EE, Jensen RT, Mantey SA, McHugh PR, Moran TH. Receptor heterogeneity for bombesin-like peptides in the rat central nervous system. Brain Res. 1990 Dec 24;537(1-2):233-40.PMID: 1964836
 * Schwartz GJ, Moran TH, McHugh PR. Autoradiographic and functional development of gastric cholecystokinin receptors in the rat. Peptides. 1990 Nov-Dec;11(6):1199-203.PMID: 2087440
 * Moran TH, Norgren R, Crosby RJ, McHugh PR.Central and peripheral vagal transport of cholecystokinin binding sites occurs in afferent fibers. Brain Res. 1990 Aug 27;526(1):95-102.PMID: 2078822
 * Nestadt G, Romanoski AJ, Chahal R, Merchant A, Folstein MF, Gruenberg EM, McHugh PR. An epidemiological study of histrionic personality disorder. Psychol Med. 1990 May;20(2):413-22.PMID: 2356266
 * Hostetler AM, McHugh PR, Moran TH. Bombesin affects feeding independent of a gastric mechanism or site of action. Am J Physiol. 1989 Nov;257(5 Pt 2):R1219-24.PMID: 2589546
 * McHugh PR. Curt Richter and Johns Hopkins: a union of assets. Am J Physiol. 1989 Jun;256(6 Pt 2):R1169-70.  PMID: 2660599
 * McHugh PR, Moran TH, Killilea M. The approaches to the study of human disorders in food ingestion and body weight maintenance. Ann N Y Acad Sci. 1989;575:1-11; discussion 11-2. Review.  PMID: 2699181
 * Margolis RL, Moran TH, McHugh PR. In vitro response of rat gastrointestinal segments to cholecystokinin and bombesin. Peptides. 1989 Jan-Feb;10(1):157-61.PMID: 2748418
 * Moran TH, Shnayder L, Hostetler AM, McHugh PR. Pylorectomy reduces the satiety action of cholecystokinin. Am J Physiol. 1988 Dec;255(6 Pt 2):R1059-63.PMID: 3202221
 * Robinson PH, Moran TH, McHugh PR. Cholecystokinin inhibits independent ingestion in neonatal rats. Am J Physiol. 1988 Jul;255(1 Pt 2):R14-20.PMID: 3394837
 * Moran TH, Moody TW, Hostetler AM, Robinson PH, Goldrich M, McHugh PR. Distribution of bombesin binding sites in the rat gastrointestinal tract. Peptides. 1988 May-Jun;9(3):643-9.PMID: 2843836
 * Moran TH, McHugh PR. Gastric and nongastric mechanisms for satiety action of cholecystokinin. Am J Physiol. 1988 Apr;254(4 Pt 2):R628-32.PMID: 3354711
 * Romanoski AJ, Nestadt G, Chahal R, Merchant A, Folstein MF, Gruenberg EM, McHugh PR. Interobserver reliability of a "Standardized Psychiatric Examination" (SPE) for case ascertainment (DSM-III). J Nerv Ment Dis. 1988 Feb;176(2):63-71.PMID: 3339343
 * Robinson PH, McHugh PR, Moran TH, Stephenson JD. Gastric control of food intake. J Psychosom Res. 1988;32(6):593-606. Review.PMID: 3065484
 * McHugh PR. William Osler and the new psychiatry. Ann Intern Med. 1987 Dec;107(6):914-8.PMID: 3318611
 * McHugh PR. Psychiatry and its scientific relatives: "a little more than kin and less than kind". J Nerv Ment Dis. 1987 Oct;175(10):579-83.  PMID: 3655766
 * Moran TH, Smith GP, Hostetler AM, McHugh PR. Transport of cholecystokinin (CCK) binding sites in subdiaphragmatic vagal branches. Brain Res. 1987 Jul 7;415(1):149-52.PMID: 2441809
 * Robinson PH, Moran TH, Goldrich M, McHugh PR. Development of cholecystokinin binding sites in rat upper gastrointestinal tract. Am J Physiol. 1987 Apr;252(4 Pt 1):G529-34.PMID: 3565569
 * McHugh PR, Moran TH. The inhibition of feeding produced by direct intraintestinal infusion of glucose: is this satiety? Brain Res Bull. 1986 Sep;17(3):415-8.PMID: 3768744
 * Robinson PH, Moran TH, McHugh PR. Inhibition of gastric emptying and feeding by fenfluramine. Am J Physiol. 1986 May;250(5 Pt 2):R764-9.PMID: 3706564
 * McHugh PR, Moran TH. The stomach, cholecystokinin, and satiety. Fed Proc. 1986 Apr;45(5):1384-90.PMID: 3956759
 * Moran TH, Robinson PH, Goldrich MS, McHugh PR. Two brain cholecystokinin receptors: implications for behavioral actions. Brain Res. 1986 Jan 1;362(1):175-9.PMID: 3002550
 * Folstein MF, Romanoski AJ, Nestadt G, Chahal R, Merchant A, Shapiro S, Kramer M, Anthony J, Gruenberg EM, McHugh PR. Brief report on the clinical reappraisal of the Diagnostic Interview Schedule carried out at the Johns Hopkins site of the Epidemiological Catchment Area Program of the NIMH. Psychol Med. 1985 Nov;15(4):809-14.PMID: 4080884
 * Slavney PR, McHugh PR. The life-story method in psychotherapy and psychiatric education: the development of confidence. Am J Psychother. 1985 Jan;39(1):57-67.PMID: 3985228
 * Folstein MF, Robinson R, Folstein S, McHugh PR. Depression and neurological disorders. New treatment opportunities for elderly depressed patients. J Affect Disord. 1985;Suppl 1:S11-4.  PMID: 2936781
 * Smith GT, Moran TH, Coyle JT, Kuhar MJ, O'Donahue TL, McHugh PR. Anatomic localization of cholecystokinin receptors to the pyloric sphincter. Am J Physiol. 1984 Jan;246(1 Pt 2):R127-30.PMID: 6320669
 * McHugh PR. The control of gastric emptying. J Auton Nerv Syst. 1983 Oct;9(1):221-31.PMID: 6663010
 * McHugh PR, Robinson RG. The two-way trade—psychiatry and neuroscience. Br J Psychiatry. 1983 Sep;143:303-5.  PMID: 6138113
 * Wirth JB, McHugh PR. Gastric distension and short-term satiety in the rhesus monkey. Am J Physiol. 1983 Aug;245(2):R174-80.PMID: 6881376
 * Brener W, Hendrix TR, McHugh PR. Regulation of the gastric emptying of glucose. Gastroenterology. 1983 Jul;85(1):76-82.PMID: 6852464
 * McHugh PR, Moran TH, Wirth JB. Postpyloric regulation of gastric emptying in rhesus monkeys. Am J Physiol. 1982 Sep;243(3):R408-15.PMID: 7114297
 * Hunt JN, McHugh PR. Does calcium mediate the slowing of gastric emptying in primates? Am J Physiol. 1982 Sep;243(3):G200-3.PMID: 6810711
 * Moran TH, McHugh PR. Cholecystokinin suppresses food intake by inhibiting gastric emptying. Am J Physiol. 1982 May;242(5):R491-7.PMID: 7081475
 * McHugh PR, Slavney PR. Methods of reasoning in psychopathology: conflict and resolution. Compr Psychiatry. 1982 May-Jun;23(3):197-215.   PMID: 7083848
 * Tune LE, McHugh PR, Coyle JT. Drug management in chronic schizophrenia. Johns Hopkins Med J. 1982 Jan;150(1):45-8.  PMID: 7054584
 * Pearlson GD, Veroff AE, McHugh PR. The use of computed tomography in psychiatry: recent applications to schizophrenia, manic-depressive illness and dementia syndromes. Johns Hopkins Med J. 1981 Nov;149(5):194-202.   PMID: 7311259
 * Moran TH, McHugh PR. Distinctions among three sugars in their effects on gastric emptying and satiety. Am J Physiol. 1981 Jul;241(1):R25-30.PMID: 7246798
 * Rabins PV, Tune LE, McHugh PR. Tardive dyskinesia. Johns Hopkins Med J. 1981 May;148(5):206-11.   PMID: 6112284
 * Tune LE, McHugh PR, Coyle JT. Management of extrapyramidal side effects induced by neuroleptics. Johns Hopkins Med J. 1981 Mar;148(3):149-53.  PMID: 7206408
 * Robinson RG, Folstein MF, Simonson M, McHugh PR. Differential antianxiety response to caloric intake between normal and obese subjects. Psychosom Med. 1980 Jul;42(4):415-27.PMID: 7443938
 * McHugh PR, Moran TH. Calories and gastric emptying: a regulatory capacity with implications for feeding. Am J Physiol. 1979 May;236(5):R254-60.PMID: 109014
 * McHugh PR. Aspects of the control of feeding: application of quantitation in psychobiology. Johns Hopkins Med J. 1979 May;144(5):147-55.PMID: 109695
 * Robinson RG, Folstein MF, McHugh PR. Reduced caloric intake following small bowel bypass surgery: a systematic study of possible causes. Psychol Med. 1979 Feb;9(1):37-53.PMID: 424487
 * McHugh PR, Folstein MF. Psychopathology of dementia: implications for neuropathology. Res Publ Assoc Res Nerv Ment Dis. 1979;57:17-30.   PMID: 368926
 * McHugh PR, Moran TH. Accuracy of the regulation of caloric ingestion in the rhesus monkey. Am J Physiol. 1978 Jul;235(1):R29-34.PMID: 98062
 * Folstein MF, McHugh PR. Defective long-term caloric regulation in obesity. NIDA Res Monogr. 1978 Jul;(20):182-8.PMID: 101852
 * Slavney RP, McHugh PR. Hysteria and Briquet's syndrome. Am J Psychiatry. 1978 Jun;135(6):759-60.   PMID: 655298
 * Slavney PR, Rich GB, Pearlson GD, McHugh PR. Phencyclidine abuse and symptomatic mania. Biol Psychiatry. 1977 Oct;12(5):697-700. PMID: 588649
 * Folstein MF, Maiberger R, McHugh PR. Mood disorder as a specific complication of stroke. J Neurol Neurosurg Psychiatry. 1977 Oct;40(10):1018-20.PMID: 591971
 * Folstein MF, Folstein SE, McHugh PR. Cognitive defect in medical illness. Ann Intern Med. 1977 Jun;86(6):827-8. PMID: 869368
 * Sovner RD, McHugh PR. Bipolar course in schizo-affective illness. Biol Psychiatry. 1976 Apr;11(2):195-204.PMID: 971445
 * Gibbs J, Falasco JD, McHugh PR. Cholecystokinin-decreased food intake in rhesus monkeys. Am J Physiol. 1976 Jan;230(1):15-18.PMID: 814821
 * Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 Nov;12(3):189-98. PMID: 1202204
 * McHugh PR, Moran TH, Barton GN. Satiety: a graded behavioural phenomenon regulating caloric intake. Science. 1975 Oct 10;190(4210):167-9.PMID: 1166310
 * McHugh PR, Gibbs J, Falasco JD, Moran T, Smith GP. Inhibitions of feeding examined in rhesus monkeys with hypothalamic disconnexions. Brain. 1975 Sep;98(3):441-54.PMID: 810215
 * Robinson RG, McHugh PR, Folstein MF. Measurement of appetite disturbances in psychiatric disorders. J Psychiatr Res. 1975 Apr;12(1):59-68. PMID: 1056477
 * Slavney PR, McHugh PR. The hysterical personality. An attempt at validation with the MMPI. Arch Gen Psychiatry. 1975 Feb;32(2):186-90.PMID: 234726
 * Von Grieff H, McHugh PR, Stokes PE. The familial history in sixteen males with bipolar manic-depressive illness. Proc Annu Meet Am Psychopathol Assoc. 1975;(63):233-9. PMID: 1242227
 * Robinson RG, McHugh PR, Bloom FE. Chlorpromazine induced hyperphagia in the rat. Psychopharmacol Commun. 1975;1(1):37-50.PMID: 1223991
 * Breakey WR, Goodell H, Lorenz PC, McHugh PR. Hallucinogenic drugs as precipitants of schizophrenia. Psychol Med. 1974 Aug;4(3):255-61. PMID: 4427973
 * Luria RE, McHugh PR. Reliability and clinical utility of the "Wing" Present State examination. Arch Gen Psychiatry. 1974 Jun;30(6):866-71. PMID: 4832191
 * Slaveny PR, McHugh PR. The hysterical personality. A controlled study. Arch Gen Psychiatry. 1974 Mar;30(3):325-9. PMID: 4813136
 * Sovner RD, McHugh PR. Lithium in the treatment of periodic catatonia: a case report. J Nerv Ment Dis. 1974 Mar;158(3):214-21. PMID: 4815670
 * Folstein M, Folstein S, McHugh PR. Clinical predictors of improvement after electroconvulsive therapy of patients with schizophrenia, neurotic reactions, and affective disorders. Biol Psychiatry. 1973 Oct;7(2):147-52. PMID: 4748846
 * McHugh PR, Gibbs J. Aspects of subcortical organization of feeding revealed by hypothalamic disconnexions in Macaca mulatta. Brain. 1972;95(2):279-92. PMID: 4347630
 * McHugh PR, Goodell H. Suicidal behavior. A distinction in patients with sedative poisoning seen in a general hospital. Arch Gen Psychiatry. 1971 Nov;25(5):456-64PMID: 5133820
 * Andersen AE, McHugh PR. Oat cell carcinoma with hypercortisolemia presenting to a psychiatric hospital as a suicide attempt. J Nerv Ment Dis. 1971 Jun;152(6):427-31. PMID: 4327364
 * McHugh PR. Hypothalamic controls on feeding behavior as revealed by a "disconnection" method. Trans Am Neurol Assoc. 1970;95:100-3. PMID: 4998755
 * Reis DJ, McHugh PR. Hypoxia as a cause of bradycardia during amygdala stimulation in monkey. Am J Physiol. 1968 Mar;214(3):601-10. PMID: 4966348
 * McHugh PR, Smith GP. Negative feedback in adrenocortical response to limbic stimulation in Macaca mulatta. Am J Physiol. 1967 Dec;213(6):1445-50. PMID: 4965485
 * Smith GP, McHugh PR. Gastric secretory response to amygdaloid or hypothalamic stimulation in monkeys. Am J Physiol. 1967 Sep;213(3):640-4. PMID: 4962493
 * McHugh PR, Smith GP. Plasma 17-OHCS response to amygdaloid stimulation with and without afterdischarges. Am J Physiol. 1967 Mar;212(3):619-22.  PMID: 4960173
 * McHugh PR. Hydrocephalic dementia. Bull N Y Acad Med. 1966 Oct;42(10):907-17. PMID: 5231976
 * McHugh PR, Black WC, Mason JW. Some hormonal responses to electrical self-stimulation in the Macaca mulatta. Am J Physiol. 1966 Jan;210(1):109-13. PMID: 4955255
 * McHugh PR. Occult Hydrocephalus. Q J Med. 1964 Apr;33:297-308. PMID: 14152976
 * McHugh PR. [THE DECEMBER PLENUM OF THE CENTRAL COMMITTEE OF THE COMMUNIST PARTY OF THE USSR AND PROBLEMS OF CHEMISTRY IN RADIOBIOLOGY.]  Radiobiologiia. 1964;4:185. Russian. PMID: 14152977
 * Hays RM, McHugh PR, Williams HE. Absence of thirst in association with hydrocephalus. N Engl J Med. 1963 Aug 1;269:227-31. PMID: 13963604
 * Gibbons JL, McHugh PR. Plasma cortisol in depressive illness. J Psychiatr Res. 1962 Sep;1:162-71.