Brodmann area 25

Human
Brodmann area 25 (BA25) is an area in the cerebral cortex of the brain and delineated based on its cytoarchitectonic characteristics. It is also called the subgenual area or area subgenualis. It is the 25th "Brodmann area" defined by Korbinian Brodmann (thus its name). BA25 is located in the cingulate region as part of the subcallosal area.

One study has noted that BA25 is metabolically overactive in treatment-resistant depression and has found that chronic deep brain stimulation in the white matter adjacent to the area is a successful antidepressant for some patients.

Guenon
Area 25 of Brodmann-1909 is a subdivision of the cerebral cortex of the guenon defined on the basis of cytoarchitecture and topology (Brodmann-1909). While Brodmann did not include it in the illustration of the guenon cortex, he described it as a portion of area 24 of Brodmann-1905 that was homologous to the subgenual area 25 of the human and that appears as Brodmann's area 25 in a topologically homologous location in Vogt-87. Note that Brodmann earlier assigned the number 25 to area 32 of Brodmann-1909 (Brodmann-1905 and Mauss-1908).

External reference

 * Douglas M. Bowden and others, Subgenual area 25, BrainInfo.
 * Helen S. Mayberg and others, "Deep brain stimulation for treatment-resistant depression", Neuron, volume 45, 2005. and "Defining Neruocircuits in Depression", Psychiatric Annals, volume 36, number 4, April 2006.
 * Brodmann area 24 in guenon from BrainInfo