2C-T-17

2C-T-17 or 2,5-dimethoxy-4-(β-isobutylthio)phenethylamine is a psychedelic phenethylamine of the 2C family. It was presumably first synthesized by Alexander Shulgin and reported in his book PIHKAL.

Chemistry
2C-T-17 is the 2 carbon homologue of Aleph-17, which has never been synthesized. The full chemical name is 2-[4-(2-isobutylthio)-2,5-dimethoxyphenyl]ethanamine. The drug has structural properties similar to drugs in the 2C-T series, with the most closely related compounds being 2C-T-7 and 2C-T-8.

General Information
The dosage range of 2C-T-17 is typically 60-100 mg and its duration is approximately 10-15 hours according to Shulgin. 2C-T-17 has highly psychedelic effects on thinking, but produces few or no visuals.

Pharmacology
The mechanism that produces 2C-T-17’s hallucinogenic and entheogenic effects has not been specifically established, however it is most likely to result from action as a 5-HT2A serotonin receptor agonist in the brain, a mechanism of action shared by all of the hallucinogenic tryptamines and phenethylamines for which the mechanism of action is known.

Dangers
The toxicity of 2C-T-17 is not well documented. 2C-T-17 is much less potent than 2C-T-7, but it may be expected that at very high doses it would display similar toxicity to that of other phenethylamines of the 2C-T family. Other phenethylamine derivatives substituted with an alkylthio group at the 4 position such as 2C-T-7 and 4-MTA are known to act as selective monoamine oxidase A inhibitors, a side effect which can lead to lethal serotonin syndrome when they are combined with stimulant drugs. Most confirmed fatalities involving 2C-T drugs involve their combination with other hard drugs such as alcohol, ecstasy or cocaine.

Legality
2C-T-17 is not illegal, but possession and sales of 2C-T-17 could be prosecuted under the Federal Analog Act because of its structural similarities to 2C-T-7.