Cholesterol side-chain cleavage enzyme

Cytochrome P450, family 11, subfamily A, polypeptide 1, also known as CYP11A1, is a human gene.

P450 scc (or 20,22-Desmolase) is an enzyme associated with the conversion of cholesterol to pregnenolone. The terminology "Desmolase" is becoming outdated and the enzyme is now more commonly referred to as P450scc.

The "scc" refers to side chain cleavage.

Pathology
A deficiency can lead to lipoid congenital adrenal hyperplasia. However, this is very rare.