Bipolar disorder - Genetic factors

Family studies
The role of genetic factors in bipolar disorder is indicated by concordance in monozygotic and dizygotic twins, respectively, of 57% and 14%, and the correlation between adopted people and their biological relatives (Cadoret, 1978).

Genetic mapping
Studies have explored the relationship between bipolar disorder and a large number of human chromosomes:


 * Bipolar disorder - Genetic linkage to chromosome 2
 * Bipolar disorder - Genetic linkage to chromosome 3p
 * Bipolar disorder - Genetic linkage to chromosome 4
 * Bipolar disorder - Genetic linkage to chromosome 5
 * Bipolar disorder - Genetic linkage to chromosome 6
 * Bipolar disorder - Genetic linkage to chromosome 8
 * Bipolar disorder - Genetic linkage to chromosome 9
 * Bipolar disorder - Genetic linkage to chromosome 11
 * Bipolar disorder - Genetic linkage to chromosome 12q
 * Bipolar disorder - Genetic linkage to chromosome 17
 * Bipolar disorder - Genetic linkage to chromosome 18
 * Bipolar disorder - Genetic linkage to chromosome 20
 * Bipolar disorder - Genetic linkage to chromosome 21
 * Bipolar disorder - Genetic linkage to chromosome 22

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Papers
Cadoret, R. J.(1978). Evidence for genetic inheritance of primary affective disorder in adoptees. Am. J. Psychiat. 135: 463-466, PubMed: 637144

Papers

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