Neuroimmune System

By definition the neuroimmune system is comprised of the immune system and those components of the nervous system that modulate immune response. In practice, the neuroimmune system also includes hormonal signals and cytokines that participate in signalling between the immune and nervous systems.

Structure
See the article on the immune system for the structure the immune system.

The key components of the nervous system that interact with the immune system are:
 * Hypothalamus
 * Pituitary gland
 * Vagus nerve

The key components of the endocrine system that interact with the immune system are:
 * Adrenals

Signals
Hormonal signaling between the nervous system and immune system is provided by:
 * Corticosteriods

Cytokine signaling between the nervous system and immune system is provided by:
 * Opiods

Overview of Neuro-Immune Interactions
Cytokines regulate immune responses, possibly through activation of the hypothalamic-pituitary-adrenal (HPA) axis.