Dopamine metabolites

Dopamine metabolites are the products following the breakdown of Dopamine



Dopamine is inactivated by reuptake via the dopamine transporter, then enzymatic breakdown by catechol-O-methyl transferase (COMT) and monoamine oxidase (MAO). Dopamine that is not broken down by enzymes is repackaged into vesicles for reuse.

Dopamine may also simply diffuse away from the synapse, and help to regulate blood pressure.