Mononeuritis multiplex

Mononeuritis multiplex is the clinical picture that arises from problems with multiple individual nerves serially or almost simultaneously.

Synonyms
Mononeuropathy multiplex

Clinical findings
Mononeuritis multiplex typically presents with the acute or subacute evolution of loss of sensory and motor function of individual peripheral nerves. The pattern of involvement is asymmetric.

Diagnosis
Electrodiagnostic studies will show multifocal sensory motor axonal neuropathy.

Causes and associations

 * diabetes mellitus
 * vasculitides
 * polyarteritis nodosa
 * Wegener granulomatosis
 * Churg-Strauss syndrome
 * immune-mediated diseases
 * rheumatoid arthritis
 * SLE
 * sarcoidosis
 * infections
 * leprosy
 * Lyme disease
 * HIV
 * amyloidosis
 * cryoglobulinemia