C fiber

C-fibers are part of the human sensory system, the part of the nervous system responsible for processing sensory information.

They are unmyelinated and as a result, have a slower conduction velocity than other nerve fibers, lower than 2 m/s. These fibers are associated with chronic or dull pain. C-fibers are associated with sensations of warmth, as well as mechanical and chemical stimuli. The density for cold receptors in the skin is greater than the density of warm-receptors (by a factor of 5). It is thought that most or all C fibers are nociceptors (responding only to noxious stimuli).

C fibers terminate in the substantia gelatinosa of Rolando.