National Center for Biotechnology Information

The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health. The NCBI is located in Bethesda, Maryland and was founded in 1988. The NCBI houses genome sequencing data in GenBank and an index of biomedical research articles in PubMed Central and PubMed, as well as other information relevant to biotechnology. All these databases are available online through the Entrez search engine.

The NCBI is directed by David Lipman, one of the original authors of the BLAST sequence alignment program and a widely respected figure in Bioinformatics. He also leads an intramural research program, including groups led by Stephen Altschul (another BLAST co-author), David Landsman, and Eugene Koonin (a prolific author on comparative genomics).

NCBI Bookshelf
The NCBI Bookshelf is a collection of freely available, on-line versions of selected biomedical books. As of March 2006, the Bookshelf had 55 titles covering aspects of molecular biology, biochemistry, cell biology, genetics, microbiology, a couple of disease states from a molecular and cellular point of view, research methods, and virology. The Bookshelf is a complement to the Entrez PubMed repository of peer-reviewed publication abstracts in that Bookshelf contents provide established perspectives on evolving areas of study and a context in which many disparate individual pieces of reported research can be organized.